This is a synthetic peptide designed for use in combination with anti-YWHAZ antibody (Catalog #: ARP48046_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
YWHAZ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and sheep orthologs. The protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for this gene.
Alias Symbols: KCIP-1, MGC111427, MGC126532, MGC138156, YWHAD, 14-3-3-zeta
Protein Interaction Partner: AANAT,AKT1,CBL,CDC25B,HCVgp1,IGF1R,MAPKAPK2,MAPT,RAF1,SSH1,SSH1,SSH2,SSH3,TSC2,UCP2,UCP3,YWHAZ,AKT1,EGFR,MAPKAPK2,YWHAZ,AANAT,ABL1,ADAM22,ADRA2A,ADRA2B,ADRA2C,AKAP13,AKT1,ARHGEF2,ATP5A1,ATXN1,BAD,BCAR1,BCR,BRAF,BSPRY,C22orf9,CBL,CDC25A,CDC25B,CDC25C,CDK16,CDK17,CENPJ,CFL1,CLIC4,CRTC2,CSF2RB,CSNK1A1,DFFA,EGFR,ENO1,EPB41L1,EPB41L3,FOXO1,FOXO3,FOXO4,GABBR1,GP1BA,GP1BB,GP5,HDAC4,HMGN1,HSPA1A,HSPA1B,IGF1R,IL9R,ING1,INPP5A,IRS1,IRS2,KCNK15,KCNK3,KCNK9,KIAA1377,KIF1C,KIF5B,KLC2,KLC4,KRT18,KSR1,LARP1,LIMK1,MAP3K2,MAP3K3,MAP3K5,MAPK8,MAPKAPK2,MAPT,MARK2,MARK3,MARK4,MDM4,MINK1,MLF1,MST1R,NFATC2,NFATC4,NR4A1,PAK4,PARD3,PARD6A,PARD6B,PDC,PFKFB2,PPP1CC,PRKCA,PRKCD,PRKCI,PRLR,PTPN13,RAF1,RALGPS2,REM1,RGS3,RIN1,RRAD,SIK1,SIK3,SLC8A2,STK25,STK38,TBXA2R,TH,TJP2,TLK2,TNFAIP3,TP53,TPD52L1,TPH1,TRA2B,TRIM21,TSC1,TSC2,TUBB,UBB,UCP2,UCP3,VIM,WEE1,XRCC6,YWHAE,YWHAZ,AANAT,AKT1,BAD,BCAR1,BRAF,C22orf9,CBL,CDC25A,CDC25B,CDK16,CSF2RB,DFFA,EDC3,EPB41L3,FOXO1,FOXO3,GP1BA,GP1BB,HDAC4,HDAC7,HMGN1,HNRNPL,HRR25,IL9R,INPP5A,KIAA1377,KIF5B,KLC1,KLC4,LARP1,LIMK1,LYST,MAP3K5,MAPT,MEPCE,Mlxipl,NADK,NCKAP1,NFATC4,NOLC1,PABPC4,PAK4,PRKCA,PRKCD,PRKCE,PRKCI,PRKCZ,PRKD1,RAF1,RAI14,RALGPS2,REM1,RGS3,RPL31,RRAD,SAMD4B,SF3B1,SYN2,TERT,TJP2,TNFAIP3,TP53,TPH1,TRA2B,TSC1,TSC2,UCP2,UCP3,USP8,Usp8,VIM,XRCC6,YWHAZ