Transmembrane Protein 173 (TMEM173) (Middle Region) Peptide
TMEM173
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all STING/TMEM173 (TMEM173) products
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- DPNIRFLDKL PQQTGDHAGI KDRVYSNSIY ELLENGQRAG TCVLEYATPL
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-TMEM173 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- 别名
- ERIS Peptide, MITA Peptide, MPYS Peptide, NET23 Peptide, STING Peptide, 2610307O08Rik Peptide, Mita Peptide, RGD1562552 Peptide, transmembrane protein 173 Peptide, TMEM173 Peptide, Tmem173 Peptide
- 背景
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This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Alias Symbols: ERIS, MITA, MPYS, SAVI, NET23, STING, hMITA, hSTING
Protein Size: 379 - 分子量
- 42 kDa
- 基因ID
- 340061
- NCBI登录号
- NM_198282, NP_938023
- UniProt
- Q86WV6
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