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Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) Peptide

TGM2 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN985039
发货至: 中国
  • 抗原 See all Transglutaminase 2 (TGM2) products
    Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))
    宿主
    资源
    • 10
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-TGM2 antibody (Catalog #: ARP47472_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))
    别名
    G-ALPHA-h Peptide, GNAH Peptide, TG2 Peptide, TGC Peptide, tgm2 Peptide, zgc:101081 Peptide, TgaseII Peptide, TGM2 Peptide, fc12b04 Peptide, wu:fc12b04 Peptide, zgc:136700 Peptide, TGL2 Peptide, G[a]h Peptide, TGase2 Peptide, tTG Peptide, tTGas Peptide, transglutaminase 2 Peptide, transglutaminase 2, C polypeptide A Peptide, transglutaminase 2b Peptide, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) Peptide, transglutaminase 2, C polypeptide Peptide, TGM2 Peptide, tgm2a Peptide, Tgm2 Peptide, tgm2b Peptide
    背景
    Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, TGM2 is the autoantigen implicated in celiac disease.Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: TG2, TGC, GNAH, G-ALPHA-h

    Protein Interaction Partner: HTT,KPNA4,ACTB,ALDOA,ANXA1,CASP3,EIF5A,FN1,GSTP1,HIST1H2BG,HIST2H2BE,HTT,ITGB1,ITGB3,KPNA3,KPNA4,LTBP1,MAP3K12,PLCD1,PPHLN1,RB1,RHOA,S100A7,SERPINF2,SMAD2,SMAD3,SPARC,TGM2,TMSB4X,TUBB,FN1,GSTP1,KPNA4,PLCD1,RB1,TGM2

    Protein Size: 687
    分子量
    77 kDa
    基因ID
    7052
    NCBI登录号
    NM_004613, NP_004604
    UniProt
    P21980
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