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serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1) Peptide

SPTLC1 适用: 人 宿主: 合成 BP, WB, IHC
产品编号 ABIN984391
发货至: 中国
  • 抗原 See all SPTLC1 products
    SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
    宿主
    资源
    • 4
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-SPTLC1 antibody (Catalog #: ARP46721_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
    别名
    ATSPT1 Peptide, SERINE PALMITOYLTRANSFERASE 1 Peptide, serine palmitoyltransferase 1 Peptide, Afu6g00300 Peptide, HSAN1 Peptide, HSN1 Peptide, LBC1 Peptide, LCB1 Peptide, SPT1 Peptide, SPTI Peptide, wu:fc75h04 Peptide, wu:fp41c08 Peptide, zgc:112247 Peptide, AW552086 Peptide, C77762 Peptide, E030036H05 Peptide, Lcb1 Peptide, RGD1306617 Peptide, Spt1 Peptide, serine palmitoyltransferase 1 Peptide, Serine palmitoyltransferase 1 Peptide, serine palmitoyltransferase long chain base subunit 1 Peptide, serine palmitoyltransferase, long chain base subunit 1 Peptide, serine palmitoyltransferase, long chain base subunit 1 L homeolog Peptide, SPT1 Peptide, AFUA_6G00300 Peptide, PAS_FragB_0040 Peptide, SPTLC1 Peptide, sptlc1 Peptide, sptlc1.L Peptide, Sptlc1 Peptide
    背景
    Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. SPTLC1 is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in SPTLC1 gene were identified in patients with hereditary sensory neuropathy type 1.Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified.

    Alias Symbols: HSAN, HSAN1, HSN1, LBC1, LCB1, MGC14645, SPT1, SPTI, hLCB1

    Protein Interaction Partner: ABCA1,SPTLC2,C20orf24,MAGED1,ORMDL3,RGS20

    Protein Size: 473
    分子量
    53 kDa
    基因ID
    10558
    NCBI登录号
    NM_006415, NP_006406
    UniProt
    O15269
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