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Suppressor of Cytokine Signaling 1 (SOCS1) (Middle Region) Peptide

SOCS1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN984227
发货至: 中国
  • 抗原 See all SOCS1 products
    SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 6
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    RQRNCFFALS VKMASGPTSI RVHFQAGRFH LDGSRESFDC LFELLEHYVA
    产品特性
    This is a synthetic peptide designed for use in combination with anti-SOCS1 Antibody(ARP42148_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))
    别名
    socs1 Peptide, zgc:91868 Peptide, jab Peptide, cis1 Peptide, ssi1 Peptide, tip3 Peptide, cish1 Peptide, ssi-1 Peptide, socs-1 Peptide, SOCS1 Peptide, LOC100228306 Peptide, socs1b Peptide, CIS1 Peptide, CISH1 Peptide, JAB Peptide, SOCS-1 Peptide, SSI-1 Peptide, SSI1 Peptide, TIP3 Peptide, Cish1 Peptide, Cish7 Peptide, Socs-1 Peptide, suppressor of cytokine signaling 1a Peptide, suppressor of cytokine signaling 1 Peptide, suppressor of cytokine signaling 1 L homeolog Peptide, socs1a Peptide, socs1 Peptide, SOCS1 Peptide, socs1.L Peptide, Socs1 Peptide
    背景
    SOCS1 is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. SOCS1 functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of its gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

    Alias Symbols: CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3

    Protein Interaction Partner: AXL,CSF1R,FLT3,FYN,GRB2,IGF1R,INSR,ITK,KIT,NCK1,PDGFRB,PIK3R2,TEK,VAV1,VAV2,AXL,COMMD1,CSF1,CSF1R,CXCR4,EGFR,FLT3,FYN,GHR,GRB2,IFNGR1,IGF1R,IL2RB,INSR,IRS1,IRS2,ITK,JAK1,JAK2,JAK3,KIT,MPL,NCK1,PDGFRB,PIK3R1,PIK3R2,PIM2,RELA,TCEB1,TCEB2,TEC,TEK,TIRAP,TRIM8

    Protein Size: 211
    分子量
    23 kDa
    基因ID
    8651
    NCBI登录号
    NM_003745, NP_003736
    UniProt
    O15524
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