This is a synthetic peptide designed for use in combination with anti-REL antibody (Catalog #: ARP38198_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
REL is a member of the Rel/NFKB family, which also includes RELA, RELB, NFKB1, and NFKB2. These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor. The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-174 CN414487.1 2-175 175-2323 X75042.1 128-2276 2324-2457 BX111941.1 575-708 2458-2592 AA279919.1 1-135 c
Alias Symbols: C-Rel
Protein Interaction Partner: CALM1,CCNE1,ELF1,GTF2B,HSPA8,MAP3K8,MAPK8,NFKB1,NFKB2,NFKBIA,NFKBIB,NFKBIE,NKRF,NOTCH1,PPP4C,REL,RELA,SP1,TBP,TNIP2,CDK2,ELF1,GTF2B,MAP3K8,MAPK8,MTPN,NFKB1,NFKB2,NFKBIA,NFKBIB,NFKBIE,NKRF,Nfkb1,PAPOLA,PPP4C,RELA,SP1,SRF,TBK1,TBP,TNIP2