Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptide
PYHIN1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all PYHIN1 products
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-PYHIN1 antibody (Catalog #: ARP50876_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
- 别名
- IFIX Peptide, RP11-520H16.1 Peptide, 4930422C14 Peptide, AI447904 Peptide, Ifi209 Peptide, Ifix Peptide, pyrin and HIN domain family member 1 Peptide, interferon activated gene 209 Peptide, PYHIN1 Peptide, Ifi209 Peptide
- 背景
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PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Alias Symbols: IFIX, MGC23885, RP11-520H16.1
Protein Size: 452 - 分子量
- 51 kDa
- 基因ID
- 149628
- NCBI登录号
- NM_198930, NP_945148
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