This is a synthetic peptide designed for use in combination with anti-PSMD11 antibody (Catalog #: ARP32344_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC3844, S9, p44.5, Rpn6
Protein Interaction Partner: BRD7,C1orf103,C7orf64,CCDC90B,COPS6,CRMP1,EEF1A1,EEF1G,FAM190B,GAPDH,GDF9,HAP1,IGSF21,MED31,NFKB2,PTN,PTPRK,SETDB1,SMAD1,SMAD2,SMAD3,SMAD4,SMAD5,TLE1,TP53,UNC119,ZBTB16,ZHX1,BRD7,C1orf103,C7orf64,CCDC90B,COPS6,CRMP1,EEF1A1,EEF1G,FAM190B,GAPDH,GDF9,GIYD2,HAP1,IGSF21,MED31,PAAF1,PSMC4,PSMD10,PSMD13,PSMD14,PSMD6,PSMD7,PTN,PTPRK,SETDB1,TLE1,TP53,TUBB2A,UCHL5,UNC119,USP14,USP15,USP20,ZBTB16,ZHX1