PIAS1
(Protein Inhibitor of Activated STAT, 1 (PIAS1))
蛋白结构域
N-Term
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
产品特性
This is a synthetic peptide designed for use in combination with anti-PIAS1 antibody (Catalog #: ARP39231_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
PIAS1
(Protein Inhibitor of Activated STAT, 1 (PIAS1))
别名
2900068C24Rik Peptide, Ddxbp1 Peptide, GBP Peptide, DDXBP1 Peptide, GU/RH-II Peptide, ZMIZ3 Peptide, ddxbp1 Peptide, gbp Peptide, pias Peptide, pias1-A Peptide, xPAIS1 Peptide, xPIAS1 Peptide, zmiz3 Peptide, protein inhibitor of activated STAT 1 Peptide, protein inhibitor of activated STAT, 1 Peptide, protein inhibitor of activated STAT, 1a Peptide, protein inhibitor of activated STAT 1 L homeolog Peptide, PIAS1 Peptide, Pias1 Peptide, pias1a Peptide, pias1.L Peptide
背景
PIAS1 is a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis.This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DDXBP1, GBP, GU/RH-II, MGC141878, MGC141879, ZMIZ3
Protein Interaction Partner: CEBPA,CEBPE,CASP8,CSRP2,ESR1,HTNVsSgp1,SUMO1,TP53,UBE2I,AR,AXIN1,CASP8,CEBPA,CEBPE,CHUK,CREBBP,CSRP2,DCLRE1A,DDX21,DNM1,DNMT3A,ELK3,ESR1,ESR2,GATA4,GRM8,JUN,MBD1,MDM2,MSX1,NIN,NR2F2,NR3C2,NR5A1,PGR,PIAS1,PIAS2,PIAS4,PRPF40A,PTK2,PTPN1,RELA,SATB2,SERBP1,SKIL,SMAD1,SMAD4,SMAD7,SNIP1,SP3,STAT1,SUFU,SUMO1,TBP,TP53,TP73,UBE2I,ZNF76,AKT1,AR,CSRP2,DNMT3A,MX1,SIAH1,SIAH2,SP3,STAB2,STAT1,SUMO1,SUMO2,TP53,UBE2I,ZMIZ2