NR2C1
(Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
产品特性
This is a synthetic peptide designed for use in combination with anti-NR2C1 antibody (Catalog #: ARP38287_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
NR2C1
(Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
别名
TR2 Peptide, NR2C1 Peptide, dor2 Peptide, tr2-11 Peptide, xDOR2 Peptide, DKFZp468M0512 Peptide, si:dkey-183c16.2 Peptide, zgc:110672 Peptide, 4831444H07Rik Peptide, 80.3 Peptide, Eenr Peptide, Tr2-11 Peptide, Tr2 Peptide, Psg4 Peptide, TR2-11 Peptide, PSG9 Peptide, nr2c1 Peptide, nuclear receptor subfamily 2 group C member 1 Peptide, nuclear receptor subfamily 2 group C member 1 S homeolog Peptide, nuclear receptor subfamily 2, group C, member 1 Peptide, pregnancy specific beta-1-glycoprotein 4 Peptide, nuclear receptor subfamily 2 group C member 1 L homeolog Peptide, NR2C1 Peptide, nr2c1.S Peptide, nr2c1 Peptide, Nr2c1 Peptide, PSG4 Peptide, nr2c1.L Peptide
背景
The nuclear orphan receptors NR2C1 represses transcription and binds DNA as a homodimer. NR2C1 binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. NR2C1 may function as a negative modulator to suppress androgen receptor function in prostate cancer. NR2C1 may exert an important repressor in regulating ER activity in mammary glands. The nuclear orphan receptors TR2 (NR2C1) and TR4 form a heterodimer that binds to the epsilon and gamma globin promoter DR1 sites
Alias Symbols: TR2, TR2-11
Protein Interaction Partner: AR,ESR1,HDAC3,HDAC4,NR2C2,NRIP1,AR,ESR1,HDAC3,HDAC4