This is a synthetic peptide designed for use in combination with anti-MAP3K14 Antibody(ARP42161_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
Alias Symbols: FTDCR1B, HS, HSNIK, NIK
Protein Interaction Partner: CHUK,IKBKAP,IKBKB,TRAF1,TRAF2,TRAF3,TRAF5,TRAF6,ALPL,CASP8,CDC37,CHUK,EDAR,EGFR,FBL,GRB10,GRB14,GRB7,HSP90AA1,HSP90AB1,IKBKAP,IKBKB,IKBKG,MAP2K4,MAP3K14,MAP3K7,MAP3K8,MAPK3,NFKB2,PEBP1,PELI3,RIPK1,RPL30,RPL4,RPL5,RPL6,RPS11,RPS13,TRAF1,TRAF2,TRAF3,TRAF5,T