Klotho (KL) (N-Term) Peptide
KL
适用: 小鼠
宿主: 合成
BP, WB
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- 抗原 See all Klotho (KL) products
- Klotho (KL)
- 蛋白结构域
- N-Term
- 宿主
- 小鼠
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- GAAPSDSPIV VAPSGAPSPP LSSTGDVASD SYNNVYRDTE GLRELGVTHY
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-Kl Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- Klotho (KL)
- 背景
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Kl may have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. It may be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1.
Alias Symbols: alpha-kl
Protein Size: 1014 - 分子量
- 116 kDa
- 基因ID
- 16591
- NCBI登录号
- NM_013823, NP_038851
- UniProt
- O35082
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