This is a synthetic peptide designed for use in combination with anti-INPP5B antibody (Catalog #: ARP54772_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
75kDa Peptide, AW260155 Peptide, INPP5P Peptide, 5PTase Peptide, inositol polyphosphate-5-phosphatase B Peptide, type II inositol 1,4,5-trisphosphate 5-phosphatase-like Peptide, inositol polyphosphate-5-phosphatase B L homeolog Peptide, inositol polyphosphate 5-phosphatase OCRL-1 Peptide, INPP5B Peptide, LOC100224437 Peptide, inpp5b.L Peptide, LOC100159919 Peptide, Inpp5b Peptide
背景
Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B is the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus.Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.