Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (N-Term) Peptide
CXCR2
适用: 人
宿主: 合成
BP, WB
-
- 抗原 See all CXCR2 products
- CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
- 蛋白结构域
- N-Term
- 宿主
- 人
-
资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-IL8RB antibody (Catalog #: ARP41956_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
-
Chemokine (C-X-C Motif) Receptor 2 (CXCR2) peptide (Ovalbumin)
CXCR2 适用: 人 宿主: 合成 WB, Imm, SDS
Chemokine (C-X-C Motif) Receptor 2 (CXCR2) (AA 3-13) peptide (Ovalbumin)CXCR2 适用: 小鼠 宿主: 合成 WB, Imm, SDS
-
- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- 抗原
- CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
- 别名
- CD182 Peptide, CDw128b Peptide, CMKAR2 Peptide, IL8R2 Peptide, IL8RA Peptide, IL8RB Peptide, CXC-R2 Peptide, CXCR-2 Peptide, CD128 Peptide, CDw128 Peptide, Cmkar2 Peptide, Gpcr16 Peptide, IL-8Rh Peptide, IL-8rb Peptide, Il8rb Peptide, mIL-8RH Peptide, C-X-C motif chemokine receptor 2 Peptide, chemokine (C-X-C motif) receptor 2 Peptide, Cxcr2 Peptide, CXCR2 Peptide
- 背景
-
IL8RB is the receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. IL8RB binds to IL-8 with high affinity. IL8RB also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CD182, CDw128b, CMKAR2, CXCR2, IL8R2, IL8RA, IL8RB
Protein Interaction Partner: ADRA1A,ARRB1,CXCL1,CXCL2,CXCL3,CXCL5,CXCL6,CXCR1,CXCR2,GNA14,GNA15,GNAI2,GNAI3,GPRASP1,GRIA1,IL8,MYO5B,PPBP,PPP2CA,RAB11FIP2,RGS12,ST13,ARRB1,CXCR2,GTF3A,IL8,MYO5B,RAB11FIP2,Rgs12
Protein Size: 360 - 分子量
- 41 kDa
- 基因ID
- 3579
- NCBI登录号
- NM_001557, NP_001548
- UniProt
- P25025
-
You are here:
