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Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) Peptide

HNRNPL 适用: 人 宿主: 合成 BP, WB, IHC
产品编号 ABIN978114
发货至: 中国
  • 抗原 See all HNRNPL products
    HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))
    宿主
    资源
    • 7
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-HNRPL antibody (Catalog #: ARP40240_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))
    背景
    Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: P/OKcl.14, hnRNP-L, HNRPL

    Protein Interaction Partner: GSTZ1,HNRNPK,PTBP1,SLC2A2,APEX1,CSE1L,FGFR3,HMG20B,HNRNPA2B1,HNRNPK,HNRNPL,PCBP2,PJA1,PTBP1,SUMO4,APEX1,CSE1L,DOCK4,EIF2B1,FGFR3,HMG20B,HNRNPA1,HNRNPA2B1,HNRNPK,HNRNPL,KHDRBS2,Khdrbs3,PCBP2,PTBP1,PUF60,YWHAZ

    Protein Size: 589
    分子量
    65 kDa
    基因ID
    3191
    NCBI登录号
    NM_001533, NP_001524
    UniProt
    P14866
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