Blocking Peptide (BP), Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
产品特性
This is a synthetic peptide designed for use in combination with anti-HDAC6 antibody (Catalog #: ARP31451_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Alias Symbols: HD6, JM21
Protein Interaction Partner: BCL3,BCL3,BCOR,BRMS1,EP300,HDAC11,PLAA,RELB,RUNX2,SIRT2,TUBA1B,TUBA4A,TUBB,UBB,UBB,VCP,ZBTB16,BCOR,CBFA2T3,DNAJB6,DNAJB8,EEA1,EGFR,EP300,HDAC11,RELB,RUNX2,UBC,UBE2D1,UBE2D3,UBE2E1,UBE2H,ZBTB16