This is a synthetic peptide designed for use in combination with anti-GPBAR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
GPBAR1
(G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))
别名
BG37 Peptide, GPCR19 Peptide, GPR131 Peptide, M-BAR Peptide, TGR5 Peptide, Tgr5 Peptide, MGC84403 Peptide, GPBAR1 Peptide, Gpbar1 Peptide, GPCR Peptide, G protein-coupled bile acid receptor 1 Peptide, G protein-coupled bile acid receptor 1 S homeolog Peptide, GPBAR1 Peptide, Gpbar1 Peptide, gpbar1.S Peptide
背景
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.
Alias Symbols: BG37, GPCR, GPCR19, GPR131, M-BAR, MGC40597, TGR5