FADD
(Fas (TNFRSF6)-Associated Via Death Domain (FADD))
宿主
人, 小鼠
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
产品特性
This is a synthetic peptide designed for use in combination with anti-Fadd antibody (Catalog #: ARP30294_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
FADD
(Fas (TNFRSF6)-Associated Via Death Domain (FADD))
别名
MORT1 Peptide, Mort1/FADD Peptide, Mort1 Peptide, TNFRSF6 Peptide, adaptor Peptide, fadd Peptide, mort1 Peptide, xfadd Peptide, Fas associated via death domain Peptide, Fas (TNFRSF6)-associated via death domain Peptide, Fas associated via death domain S homeolog Peptide, Fas (tnfrsf6)-associated via death domain Peptide, FADD Peptide, Fadd Peptide, fadd.S Peptide, fadd Peptide
背景
Fadd is apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.