This is a synthetic peptide designed for use in combination with anti-DES antibody (Catalog #: ARP41483_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
Desmin (DES)
别名
DES Peptide, des-b Peptide, MGC80853 Peptide, des Peptide, csm1 Peptide, csm2 Peptide, desm Peptide, cmd1i Peptide, MGC75911 Peptide, LOC100220724 Peptide, desmin Peptide, cb290 Peptide, fb59a12 Peptide, wu:fb59a12 Peptide, zgc:109859 Peptide, CSM1 Peptide, CSM2 Peptide, LGMD2R Peptide, wu:fc11d08 Peptide, zgc:154009 Peptide, des-a Peptide, MGC52614 Peptide, desmin Peptide, desmin, gene 1 L homeolog Peptide, desmin, gene 1 Peptide, desmin a Peptide, desmin b Peptide, desmin, gene 1 S homeolog Peptide, desmin, gene 2 S homeolog Peptide, DES Peptide, des.1.L Peptide, des.1 Peptide, des Peptide, desma Peptide, Des Peptide, desmb Peptide, des.1.S Peptide, des.2.S Peptide
背景
DES is a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in its gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793
Protein Interaction Partner: CAPN1,AURKB,CAPN1,DSP,NEB,PKD1,ROCK1,S100A1,S100B,SHBG,SPTAN1,SYNC,SYNM,TRIM7,DSP,NEB,S100A1,SPTAN1,SYNC,SYNM