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CD3 epsilon (CD3E) (Middle Region) Peptide

CD3E 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN974673
发货至: 中国
  • 抗原 See all CD3 epsilon (CD3E) products
    CD3 epsilon (CD3E)
    蛋白结构域
    Middle Region
    宿主
    资源
    • 9
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    QYPGSEILWQ HNDKNIGGDE DDKNIGSDED HLSLKEFSEL EQSGYYVCYP
    产品特性
    This is a synthetic peptide designed for use in combination with anti-CD3E Antibody(ARP59097_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    CD3 epsilon (CD3E)
    背景
    The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

    Alias Symbols: FLJ18683, T3E, TCRE

    Protein Interaction Partner: CD3D,CD3EAP,CD3G,CD79B,LCK,NCK1,NCK2,NCL,PIK3R1,PTPN22,SHC1,SYK,TOP2B,TRAT1,UNC119,ZAP70,CD3EAP,CD3G,JAK3,NCK1,NCK2,NCL,PIK3R1,SYK,TOP2B,ZAP70

    Protein Size: 207
    分子量
    23 kDa
    基因ID
    916
    NCBI登录号
    NM_000733, NP_000724
    UniProt
    P07766
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