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CD274 (PD-L1) (C-Term) Peptide

PD-L1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN974661
发货至: 中国
  • 抗原 See all PD-L1 products
    PD-L1 (CD274 (PD-L1))
    蛋白结构域
    C-Term
    宿主
    资源
    • 6
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    ELIRDYNSSR EDSLQDAWDY VQAQVKCCGW VSFYNWTDNA ELMNRPEVTY
    产品特性
    This is a synthetic peptide designed for use in combination with anti-CD82 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    PD-L1 (CD274 (PD-L1))
    别名
    B7-H Peptide, B7H1 Peptide, PD-L1 Peptide, PDCD1L1 Peptide, PDCD1LG1 Peptide, PDL1 Peptide, A530045L16Rik Peptide, B7h1 Peptide, Pdcd1l1 Peptide, Pdcd1lg1 Peptide, Pdl1 Peptide, RGD1566211 Peptide, CD274 molecule Peptide, CD274 antigen Peptide, programmed cell death 1 ligand 2 Peptide, CD274 Peptide, Cd274 Peptide, PDCD1LG2 Peptide
    背景
    This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

    Alias Symbols: 4F9, C33, GR15, IA4, KAI1, R2, SAR2, ST6, TSPAN27

    Protein Interaction Partner: BCL3,CTNNB1,KAT5,MAP3K1,NCOR1,NFKB1,POLR2A,RUVBL1,RUVBL2,TAB2,CANX,CD19,CD4,CD63,EGFR,ERBB2,ERBB3,HBEGF,HLA-DMA,HLA-DMB,HLA-DRA,IGSF8,ITGA3,ITGA4,ITGA6,ITGB1,ITGB2,LRP1,NUP88,PTGFRN,VANGL1,CD151,CD19,CD4,CD46,CD63,CD9,EGFR,ERBB2,ERBB3,HBEGF,HLA-DMB,HLA-DO

    Protein Size: 242
    分子量
    27 kDa
    基因ID
    3732
    NCBI登录号
    NM_001024844
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