Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
产品特性
This is a synthetic peptide designed for use in combination with anti-CAV3 antibody (Catalog #: AVARP09021_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
Caveolin 3 (CAV3)
背景
CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
Alias Symbols: LQT9, VIP21, LGMD1C, VIP-21
Protein Interaction Partner: DAG1,DYSF,EGFR,GNAS,INSR,JPH2,NOS1,PFKM,SLC22A11,SLC8A1,DAG1,DYSF,EGFR,JPH2,PDGFRA,PDGFRB,PFKM,SLC8A1