Calreticulin (CALR) Peptide
CALR
适用: 人
宿主: 合成
BP, WB, IHC
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- 抗原 See all Calreticulin (CALR) products
- Calreticulin (CALR)
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-CALR antibody (Catalog #: ARP30114_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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Calreticulin (CALR) peptide (Ovalbumin)
CALR 适用: 人 宿主: 合成 WB, Imm, SDS
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- Calreticulin (CALR)
- 背景
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Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.
Alias Symbols: RO, CRT, SSA, cC1qR
Protein Interaction Partner: CALR,HLA-A,PDIA3,TSHR,APOB,APP,AR,B2M,CALR,CD1D,F5,F8,FBN1,FGB,HLA-C,ITGA2B,ITGA3,ITGAV,LPL,LRP1,MBL2,MTNR1A,NKX2-1,NR3C1,PDIA2,PDIA3,PLAT,PLP1,PRF1,SCARF1,SLC2A1,SLC6A4,SUMO4,TAPBP,TF,THBS1,TSHR,VWF,APOB,APP,AR,CANX,CD1D,CD40,ELF3,EPB41,F5,FGB,LRP1,MBL2,NKX2-1,NR3C1,PDIA3,PLAT,PRF1,SLC2A1,SLC6A4,TAPBP,TF,VWF
Protein Size: 417 - 分子量
- 48 kDa
- 基因ID
- 811
- NCBI登录号
- NM_004343, NP_004334
- UniProt
- P27797
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