This is a synthetic peptide designed for use in combination with anti-BID Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Alias Symbols: FP497, MGC15319, MGC42355
Protein Interaction Partner: BAX,BCL2,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L1,BCL2L2,BNC1,PACS2,BCL2L1,BAK1,BAX,BCL2,BCL2A1,BCL2L1,BCL2L2,BID,CAPN1,CASP1,CASP10,CASP2,CASP3,CASP8,CSNK1A1,CSNK1E,CSNK2A1,CSNK2A2,CSNK2B,GZMB,MCL1,YWHAB,ARHGDIA,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L2,BID,CAPN2,CASP10,