ATF4
(Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
产品特性
This is a synthetic peptide designed for use in combination with anti-ATF4 antibody (Catalog #: ARP38067_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
ATF4
(Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
背景
ATF4s a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.
Alias Symbols: CREB2, TXREB, CREB-2, TAXREB67
Protein Interaction Partner: DISC1,DISC1,TRIB3,CCDC106,CEBPB,CEBPG,CREBZF,DAPK3,DDIT3,DISC1,GABBR2,GPS2,GTF2F2,JUN,LDOC1,NFE2L1,NFE2L2,POLR2C,PTCD3,TREX2,TRIB3,TTR,ATF3,CCDC106,CREBBP,Cebpb,DISC1,EIF2A,GABBR1,GABBR2,GPS2,GTF2B,GTF2F2,JUN,LDOC1,POLR2C,PTCD3,TBP,TREX2,TRIB3,TTR