This is a synthetic peptide designed for use in combination with anti-ANXA6 antibody (Catalog #: ARP36582_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
Alias Symbols: AW107198, Anx6, AnxVI, Cabm, Camb, ANX6, CBP68
Protein Interaction Partner: CR2,RASA1,A2M,CDC73,CR2,RASA1,S100A1,S100B,TPD52,CDC73,CR2,RASA1,Rasa1,S100A1,S100B,tax