A synthetic peptide for use as a blocking control in assays to test for specificity of DVL1 antibody, Alternative Names: DVL1 control peptide, DVL1 antibody Blocking Peptide, Anti-DVL1 Blocking Peptide, Dishevelled Dsh Homolog 1 Blocking Peptide, DVL Blocking Peptide, MGC54245 Blocking Peptide
DVL1 is a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 gene is a candidate for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1 gene. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.