A synthetic peptide for use as a blocking control in assays to test for specificity of LEP antibody, Alternative Names: Leptin control peptide, Leptin antibody Blocking Peptide, Anti-Leptin Blocking Peptide, OB Blocking Peptide, OBS Blocking Peptide, LEP Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
Leptin (LEP)
别名
ob Peptide, obese Peptide, LEPD Peptide, OB Peptide, OBS Peptide, leptin Peptide, Lep Peptide, LEP Peptide, lep Peptide
背景
LEP is a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.