A synthetic peptide for use as a blocking control in assays to test for specificity of TXNDC4 antibody, Alternative Names: TXNDC4 control peptide, TXNDC4 antibody Blocking Peptide, Anti-TXNDC4 Blocking Peptide, Thioredoxin Domain Containing 4 Blocking Peptide, ERP44 Blocking Peptide, KIAA0573 Blocking Peptide, TXNDC4, TXNDC-4, TXNDC 4, TXNDC-4 Blocking Peptide, TXNDC 4 Blocking Peptide
TXNDC4 mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. TXNDC4 inhibits the calcium channel activity of ITPR1. TXNDC4 may have a role in the control of oxidative protein folding in the endoplasmic reticulum. TXNDC4 is required to retain ERO1L and ERO1LB in the endoplasmic reticulum.