A synthetic peptide for use as a blocking control in assays to test for specificity of JAK3 antibody, Alternative Names: JAK3 control peptide, JAK3 antibody Blocking Peptide, Anti-JAK3 Blocking Peptide, Janus Kinase 3 Blocking Peptide, JAK-3 Blocking Peptide, JAK3_HUMAN Blocking Peptide, JAKL Blocking Peptide, L-JAK Blocking Peptide, LJAK Blocking Peptide
JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases, which is involved in cytokine receptor-mediated intracellular signal transduction. JAK3 is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in JAK3 are associated with autosomal SCID (severe combined immunodeficiency disease).