A synthetic peptide for use as a blocking control in assays to test for specificity of AGK antibody, Alternative Names: AGK control peptide, AGK antibody Blocking Peptide, Anti-AGK Blocking Peptide, Acylglycerol Kinase Blocking Peptide, FLJ10842 Blocking Peptide, MULK Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
Acylglycerol Kinase (AGK)
背景
AGK is a lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. AGK does not phosphorylate sphingosine. Overexpression of AGK increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.