A synthetic peptide for use as a blocking control in assays to test for specificity of PMS2 antibody, Alternative Names: PMS2 control peptide, PMS2 antibody Blocking Peptide, Anti-PMS2 Blocking Peptide, Pms2 Postmeiotic Segregation Increased 2 Blocking Peptide, HNPCC4 Blocking Peptide, PMS2CL Blocking Peptide, PMSL2 Blocking Peptide, PMS2, PMS-2, PMS 2, PMS-2 Blocking Peptide, PMS 2 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
PMS2
(PMS2 Postmeiotic Segregation Increased 2 (S. Cerevisiae) (PMS2))
背景
PMS2 is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors.