A synthetic peptide for use as a blocking control in assays to test for specificity of DDX1 antibody, Alternative Names: DDX1 control peptide, DDX1 antibody Blocking Peptide, Anti-DDX1 Blocking Peptide, Dead Blocking Peptide, Asp-Glu-Ala-Asp Box Polypeptide 1 Blocking Peptide, DBP-RB Blocking Peptide, UKVH5d Blocking Peptide, DDX1, DDX-1, DDX 1, DDX-1 Blocking Peptide, DDX 1 Blocking Peptide
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX1 is a DEAD box protein of unknown function. It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin.