A synthetic peptide for use as a blocking control in assays to test for specificity of HK2 antibody, Alternative Names: Hexokinase 2 control peptide, Hexokinase 2 antibody Blocking Peptide, Anti-Hexokinase 2 Blocking Peptide, DKFZp686M1669 Blocking Peptide, HKII Blocking Peptide, HXK2 Blocking Peptide, HK2 Blocking Peptide, Hexokinase Type 2 Blocking Peptide, Hexokinase Type 2, Hexokinase Type -2, Hexokinase Type 2, Hexokinase Type -2 Blocking Peptide, Hexokinase Type 2 Blocking Peptide
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. HK2 (hexokinase 2) is the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this protein is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway.