A synthetic peptide for use as a blocking control in assays to test for specificity of FZD4 antibody, Alternative Names: FZD4 control peptide, FZD4 antibody Blocking Peptide, Anti-FZD4 Blocking Peptide, Frizzled Homolog 4 Blocking Peptide, EVR1 Blocking Peptide, FEVR Blocking Peptide, FZD4S Blocking Peptide, Fz-4 Blocking Peptide, FzE4 Blocking Peptide, GPCR Blocking Peptide, MGC34390 Blocking Peptide
FZD4 is a member of the frizzled family. Members of this family are seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.