A synthetic peptide for use as a blocking control in assays to test for specificity of SIRT7 antibody, Alternative Names: SIRT7 control peptide, SIRT7 antibody Blocking Peptide, Anti-SIRT7 Blocking Peptide, sirtuin, silent mating type information regulation 2 homolog 7, S. cerevisiae Blocking Peptide, MGC126840 Blocking Peptide, MGC126842 Blocking Peptide, SIR2L7 Blocking Peptide, SIRT7, SIRT-7, SIRT 7, SIRT-7 Blocking Peptide, SIRT 7 Blocking Peptide
SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family.