A synthetic peptide for use as a blocking control in assays to test for specificity of Rad21 antibody, Alternative Names: Rad21 control peptide, Rad21 antibody Blocking Peptide, Anti-Rad21 Blocking Peptide, RAD21 homolog, S. pombe Blocking Peptide, MGC116373 Blocking Peptide, Rad21 Blocking Peptide, Rad21, Rad-21, Rad 21, Rad-21 Blocking Peptide, Rad 21 Blocking Peptide
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.