A synthetic peptide for use as a blocking control in assays to test for specificity of GADD45 B antibody, Alternative Names: GADD45B control peptide, GADD45B antibody Blocking Peptide, Anti-GADD45B Blocking Peptide, Growth Arrest And Dna-Damage-Inducible Beta Blocking Peptide, DKFZP566B133 Blocking Peptide, GADD45BETA Blocking Peptide, MYD118 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
GADD45B
(Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))
别名
GADD45BETA Peptide, MYD118 Peptide, AI323528 Peptide, Myd118 Peptide, CS131 Peptide, cb196 Peptide, gadd45b Peptide, gadd45b2 Peptide, sb:cb196 Peptide, zgc:73104 Peptide, gadd45beta Peptide, wu:fa92d10 Peptide, wu:fa98h12 Peptide, wu:fk65h03 Peptide, zgc:111973 Peptide, gadd45b1 Peptide, gadd45bl Peptide, zgc:112453 Peptide, growth arrest and DNA damage inducible beta Peptide, growth arrest and DNA-damage-inducible 45 beta Peptide, growth arrest and DNA-damage-inducible, beta Peptide, growth arrest and DNA-damage-inducible, beta a Peptide, growth arrest and DNA-damage-inducible, beta b Peptide, GADD45B Peptide, Gadd45b Peptide, gadd45ba Peptide, gadd45bb Peptide
背景
GADD45B is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.