A synthetic peptide for use as a blocking control in assays to test for specificity of App antibody, Alternative Names: App control peptide, App antibody Blocking Peptide, Anti-App Blocking Peptide, amyloid beta, A4 precursor protein Blocking Peptide, Ag Blocking Peptide, Abpp Blocking Peptide, Adap Blocking Peptide, Cvap Blocking Peptide, Abeta Blocking Peptide, betaApp Blocking Peptide, AL024401 Blocking Peptide, E030013M08Rik Blocking Peptide, App Blocking Peptide
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease.