A synthetic peptide for use as a blocking control in assays to test for specificity of CENPH antibody, Alternative Names: CENPH control peptide, CENPH antibody Blocking Peptide, Anti-CENPH Blocking Peptide, Centromere Protein H Blocking Peptide, NNF1 Blocking Peptide, PMF1 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
CENPH
(Centromere Protein H (CENPH))
别名
1700021I11Rik Peptide, 2410018A12Rik Peptide, 2610042E16Rik Peptide, 2810046K12Rik Peptide, AU044255 Peptide, CENP-H Peptide, ENP Peptide, si:dkey-186m8.3 Peptide, cenp-h Peptide, centromere protein H Peptide, centromere protein H pseudogene Peptide, CENPH Peptide, Cenph Peptide, cenph Peptide, LOC100356112 Peptide, LOC101788801 Peptide
背景
Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. CENPH colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.