Presenilin 1 (PSEN1) Peptide
PSEN1
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
-
- 抗原 See all Presenilin 1 (PSEN1) products
- Presenilin 1 (PSEN1)
- 蛋白类型
- Synthetic
- 宿主
- 哺乳动物
-
资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- EGDPEAQRRV SKNSKYNAES TERESQDTVA ENDDGGFSEE WEAQRDSHLG
- 产品特性
-
A synthetic peptide for use as a blocking control in assays to test for specificity of PSEN1 antibody,
Alternative Names: PSEN1 control peptide, PSEN1 antibody Blocking Peptide, Anti-PSEN1 Blocking Peptide, presenilin 1 Blocking Peptide, AD3 Blocking Peptide, FAD Blocking Peptide, PS1 Blocking Peptide, S182 Blocking Peptide, PSEN1, PSEN-1, PSEN 1, PSEN-1 Blocking Peptide, PSEN 1 Blocking Peptide
-
-
- 应用备注
- Optimal conditions should be determined by the investigator
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C long term.
-
- 抗原
- Presenilin 1 (PSEN1)
- 背景
- Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1, PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes.
- 分子量
- 53 kDa
-
You are here:
