A synthetic peptide for use as a blocking control in assays to test for specificity of MTHFD2 antibody, Alternative Names: MTHFD2 control peptide, MTHFD2 antibody Blocking Peptide, Anti-MTHFD2 Blocking Peptide, Methylenetetrahydrofolate Dehydrogenase Blocking Peptide, Nadp+ Dependent 2 Methenyltetrahydrofolate Cyclohydrolase Blocking Peptide, NMDMC Blocking Peptide, MTHFD2, MTHFD-2, MTHFD 2, MTHFD-2 Blocking Peptide, MTHFD 2 Blocking Peptide
纯化方法
The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
MTHFD2 is a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD.