A synthetic peptide for use as a blocking control in assays to test for specificity of GPI antibody, Alternative Names: GPI control peptide, GPI antibody Blocking Peptide, Anti-GPI Blocking Peptide, glucose-6-phosphate isomerase Blocking Peptide, AMF Blocking Peptide, GNPI Blocking Peptide, NLK Blocking Peptide, PGI Blocking Peptide, PHI Blocking Peptide, SA36 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
GPI
(Glucose-6-Phosphate Isomerase (GPI))
物质类
Viral Protein
背景
This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.