A synthetic peptide for use as a blocking control in assays to test for specificity of Hdac3 antibody, Alternative Names: Hdac3 control peptide, Hdac3 antibody Blocking Peptide, Anti-Hdac3 Blocking Peptide, histone deacetylase 3 Blocking Peptide, Hdac3 Blocking Peptide, Hdac3, Hdac-3, Hdac 3, Hdac-3 Blocking Peptide, Hdac 3 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
HDAC3
(Histone Deacetylase 3 (HDAC3))
背景
Hdac3 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Hdac3 is required to repress transcription of the POU1F1 transcription factor. Hdac3 acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation.