A synthetic peptide for use as a blocking control in assays to test for specificity of MRE11 A antibody, Alternative Names: MRE11A control peptide, MRE11A antibody Blocking Peptide, Anti-MRE11A Blocking Peptide, MRE11 meiotic recombination 11 homolog A, S. cerevisiae Blocking Peptide, ATLD Blocking Peptide, HNGS1 Blocking Peptide, MRE11 Blocking Peptide, MRE11B Blocking Peptide, MRE11A, MREA-11, MREA 11, MREA-11 Blocking Peptide, MREA 11 Blocking Peptide
纯化方法
The antibody is affinity purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
Mre11 (MRE11A)
(MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
背景
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.