A synthetic peptide for use as a blocking control in assays to test for specificity of CHGA antibody, Alternative Names: Chromogranin A control peptide, Chromogranin A antibody Blocking Peptide, Anti-Chromogranin A Blocking Peptide, CGA Blocking Peptide, Parathyroid Secretory Protein 1 Blocking Peptide, CHGA Blocking Peptide
CHGA is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. Its gene product is a precursor to three biologically active peptides, vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.