Norrie Disease (Pseudoglioma) (NDP) Peptide
NDP
适用: 哺乳动物
宿主: 合成
BP, IHC, WB
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- 抗原 See all Norrie Disease (Pseudoglioma) (NDP) products
- Norrie Disease (Pseudoglioma) (NDP)
- 蛋白类型
- Synthetic
- 宿主
- 哺乳动物
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- 序列
- DPRRCMRHHY VDSISHPLYK CSSKMVLLAR CEGHCSQASR SEPLVSFSTV
- 产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of NDP antibody,
Alternative Names: NDP control peptide, NDP antibody Blocking Peptide, Anti-NDP Blocking Peptide, Norrie Disease Blocking Peptide, Pseudoglioma Blocking Peptide, EVR2 Blocking Peptide, FEVR Blocking Peptide, ND Blocking Peptide - 纯化方法
- Rabbit Anti-p44/42 MAP Kinase (Ab-202) Polyclonal Antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
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- 应用备注
- Optimal conditions should be determined by the investigator
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C long term.
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- 抗原
- Norrie Disease (Pseudoglioma) (NDP)
- 别名
- EVR2 Peptide, FEVR Peptide, ND Peptide, evr2 Peptide, fevr Peptide, xnorrin Peptide, Ndph Peptide, RGD1563968 Peptide, NDP, norrin cystine knot growth factor Peptide, Norrie disease (pseudoglioma) L homeolog Peptide, Norrie disease (pseudoglioma) (human) Peptide, NDP Peptide, ndp.L Peptide, Ndp Peptide
- 背景
- NDP activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. NDP plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. NDP acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1).
- 分子量
- 15 kDa
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