A synthetic peptide for use as a blocking control in assays to test for specificity of TCAP antibody, Alternative Names: TCAP control peptide, TCAP antibody Blocking Peptide, Anti-TCAP Blocking Peptide, Titin-Cap Blocking Peptide, Telethonin Blocking Peptide, CMD1N Blocking Peptide, LGMD2G Blocking Peptide, T-cap Blocking Peptide, TELE Blocking Peptide, telethonin Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
TCAP
(Titin-Cap (Telethonin) (TCAP))
背景
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.