A synthetic peptide for use as a blocking control in assays to test for specificity of MKNK1 antibody, Alternative Names: MKNK1 control peptide, MKNK1 antibody Blocking Peptide, Anti-MKNK1 Blocking Peptide, MAP kinase interacting serine/threonine kinase 1 Blocking Peptide, MNK1 Blocking Peptide, MKNK1, MKNK-1, MKNK 1, MKNK-1 Blocking Peptide, MKNK 1 Blocking Peptide
纯化方法
The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
MKNK1 may play a role in the response to environmental stress and cytokines. It appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.