A synthetic peptide for use as a blocking control in assays to test for specificity of CCDC139 antibody, Alternative Names: PUS10 control peptide, PUS10 antibody Blocking Peptide, Anti-PUS10 Blocking Peptide, Pseudouridylate Synthase 10 Blocking Peptide, FLJ32312 Blocking Peptide, MGC126729 Blocking Peptide, MGC126755 Blocking Peptide, PUS10, PUS-10, PUS 10, PUS-10 Blocking Peptide, PUS 10 Blocking Peptide
Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs.